Scientific Programme

The scientific programme of the Graduate Programme "Infectious Disease Research" is based on the independent research projects of individual research groups cooperating within the framework of the Institute for Molecular Infection Biology and the Junior Groups of the Research Center for Infectious Diseases.

 

Doctoral projects


Biochemical and functional characterization of novel blood stage kinases in the malaria pathogen Plasmodium falciparum

Name: Shruti Agarwal
Supervisor: PD Dr. Gabriele Pradel
Promotion Committee: PD Dr. Gabriele Pradel, Prof. Dr. Christian Doerig, Prof. Dr. Jörg Hacker


Ecological and molecular investigations of the Sponge Orange Band disease (SOB) in the Caribbean sponge Xestospongia muta

Name: Hilde Gabriele Angermeier
Supervisors: Prof. Dr. Ute Hentschel
Promotion Committee: Prof.  Dr. Ute Hentschel, Prof. Dr. Georg Krohne, Prof. Dr. Joseph R. Pawlik


Utilisation of amino acids in the human pathogen Aspergillus fumigatus

Name: Anna Bergmann
Supervisor: PD Dr. Sven Krappmann
Promotion Committee: PD Dr. Sven Krappmann, PD Dr. Knut Ohlsen, PD Dr. Jürgen Löffler
 


Regulation of morphogenesis and virulence gene expression by nitrogen availability in the fungal pathogen Candida albicans

Name: Nico Dunkel
Supervisor: Prof. Dr. Joachim Morschhäuser
Promotion Committee: Prof. Dr. Joachim Morschhäuser, PD Dr. Sven Krappmann, Prof. Dr. Roy Gross
 


Bioinformatic analyses of enterobacterial genomes and its application: Improvement of a DNA array for diagnostics of clinically relevant enterobacteria

Name: Torben Friedrich
Supervisor: Prof. Dr. Jörg Hacker / PD Dr. Ulrich Dobrindt
Promotion Committee: Prof. Dr. Jörg Hacker, Prof. Dr. Thomas Dandekar, Dr. Sven Rahmann
 


Analysis of the structural basis for DNA-specificity in pathogenicity island recombination of uropathogenic E. coli strain 536

Name: Kishore Geddam Chowdary
Supervisor: Prof. Dr. Jörg Hacker
Promotion Committee: Prof. Dr. Jörg Hacker, Prof. Dr. Caroline Kisker, PD Dr. Ulrich Dobrindt
 


Aspects of nitrogen metabolism and virulence in Aspergillus fumigatus

Name: Thomas Hartmann
Supervisor: PD Dr. Sven Krappmann
Promotion Committee: PD Dr. Sven Krappmann, PD Dr. Frank Ebel, Prof. Dr. Joachim Morschhäuser


NMR imaging for in vivo characterisation of infections

Name: Tobias Hertlein
Supervisor: PD Dr. Knut Ohlsen
Promotion Committee: PD Dr. Knut Ohlsen, Prof. Dr. Peter Jakob, Prof. Dr. Dr. Bhanu Sinha


Thesis project: Functional characterization of proteases and kinases in the blood and sexual stages of Plasmodium falciparum

Name: Selina Kern
Supervisor: PD Dr. Gabriele Pradel
Promotion Committee:
PD Dr. Sven Krappmann, Dr. Jude Przyborski
 


Improvement of molecular epidemiological strain typing of pathogenic and non-pathogenic Escherichia coli

Name: Christian-Daniel Köhler
Supervisor: PD Dr. Ulrich Dobrindt
Promotion Committee: PD Dr. Ulrich Dobrindt, Prof. Dr. Ulrich Vogel, Prof. Dr. Dag Harmsen


Structural and functional characterization of the polyketide colibactin expressed in extraintestinal pathogenic and commensal Escherichia coli

Name: Grit Krumbholz
Supervisors: Prof. Dr. Jörg Hacker / PD Dr. Ulrich Dobrindt
Promotion Committee: Prof. Dr. Jörg Hacker, Dr. Eric Oswald, PD Dr. Ulrich Dobrindt
 


Molecular interactions of the malaria parasite sexual stages during fertilization and their interplay with components of the mosquito midgut

Name: Andrea Kühn
Supervisors: PD Dr. Gabriele Pradel
Promotion Committee: PD Dr. Gabriele Pradel, Dr. Oliver Billker, Prof. Dr. Klaus Brehm


Comparative genomics and analysis of factors involved in host-pathogen interaction of Escherichia coli bovine mastitis isolates

Name: Andreas Leimbach
Supervisor:
PD Dr. Ulrich Dobrindt
Promotion Committee: PD Dr. Ulrich Dobrindt, PD Dr. Knut Ohlsen, Prof. Dr. Hans-Martin Seyfert


Analysis of Staphylococcus aureus-host interactions

Name: Birgit Lorenz
Supervisor:
PD Dr. Knut Ohlsen
Promotion Committee: PD Dr. Knut Ohlsen, Prof. Dr. Jörg Hacker, Prof. Dr. Jürgen Kreft
 


Determination of the mode of action of new drugs against Staphylococcus aureus

Name: Thomas Menzel
Supervisor:
PD Dr. Knut Ohlsen
Promotion Committee: PD Dr. Knut Ohlsen, PD Dr. Wilma Ziebuhr, PD Dr. Heike Bruhn
 


Stress resistance of the pathogenic fungus Aspergillus fumigatus via eIF2a kinase signaling

Name: Anette Schedler
Supervisor: PD Dr. Sven Krappmann
Promotion Committee: PD Dr. Sven Krappmann, PD Dr. Gabriele Pradel, PD Dr. Ulrich Dobrindt
 


The analysis of staphylococcal infections by means of new imaging techniques

Name: Tina Schäfer
Supervisor: PD Dr. Knut Ohlsen
Promotion Committee: PD Dr. Knut Ohlsen, Prof. Dr. Jörg Hacker, PD Dr. Christiane Wolz
 


Characterization of the mechanisms involved in the microevolution of asymptomatic bacteriuria Escherichia coli

Name: Ellaine Salvador
Supervisor: Prof. Dr. Jörg Hacker
Promotion Committee: Prof. Dr. Jörg Hacker, Prof. Dr. Catharina Svanborg, PD Dr. Ulrich Dobrindt


Characterization of protein glycosylation pathways in Escherichia coli

Name: Roswitha Schiller
Supervisor: PD Dr. Ulrich Dobrindt
Promotion Committee: PD Dr. Ulrich Dobrindt, Prof. Dr. M. Alexander Schmidt, Prof. Dr. Jörg Hacker


Functional analysis of a transcription factor controlling multidrug resistance in the human fungal pathogen Candida albicans

Name: Sabrina Schubert
Supervisor: Prof. Dr. Joachim Morschhäuser
Promotion Committee: Prof. Dr. Joachim Morschhäuser, Prof. Dr. Klaus Brehm, PD Dr. Knut Ohlsen


Construction of recombinant E. coli Nissle 1917 strains expressing defensins: a novel therapy for treatment of inflammatory bowel disease

Name: Ean-jeong Seo
Supervisor: Dr. Tobias Ölschläger
Promotion Committee: Dr. Tobias Ölschläger, PD Dr. Ulrich Dobrindt, Dr. Jan Wehkamp
 


Characterization of molecular interactions between sexual stage-specific proteins in Plasmodium falciparum

Name: Nina Simon
Supervisor: PD Dr. Gabriele Pradel
Promotion Committee: PD Dr. Gabriele Pradel, Dr. Pietro Alano, PD Dr. Heike Bruhn
 


The influence of the probiotic Escherichia coli strain Nissle 1917 and its flagellar system on the production of antimicrobial peptides by different human host cells

Name: Anja Troge
Supervisor: Dr. Tobias Ölschläger
Promotion Committee: Dr. Tobias Ölschläger, PD Dr. Ulrich Dobrindt, Dr. Jan Wehkamp


Characterization of virulence-associated traits of Escherichia coli bovine mastitis isolates

Name: Ingmar Zude
Supervisor:
PD Dr. Ulrich Dobrindt
Promotion Committee: PD Dr. Ulrich Dobrindt, Prof. Dr. Jörg Hacker, Dr. Eric Oswald
 

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